GHRP-6

Also known as: Growth Hormone Releasing Peptide-6

Overview

Growth hormone optimization

GHRP-6 is a synthetic hexapeptide and one of the first growth hormone releasing peptides developed. It stimulates GH secretion by activating the ghrelin receptor. Unlike later-generation peptides like ipamorelin, GHRP-6 significantly increases appetite and also stimulates cortisol and prolactin release. It has been studied for treating GH deficiency, cachexia, and age-related muscle loss.

Mechanism of Action

First-generation growth hormone secretagogue that stimulates GH release and increases appetite via ghrelin mimicry

Dosage Information

Parameter	Detail
Administration	Subcutaneous injection
Typical Dose	100-300mcg 2-3x daily
Frequency	Daily

Side Effects

Reported adverse effects from clinical data and post-market surveillance

Common Side Effects

Significant increase in appetite

Water retention

Tingling or numbness

Fatigue

Gynecomastia

Serious Side Effects

Elevated cortisol

Elevated prolactin

Insulin resistance

!Contraindications

Do not use this peptide if any of the following apply

Active cancer
Pregnancy
Children

Clinical Evidence

Evidence Quality

Emerging

Clinical Trial Phase

Preclinical / Not submitted

View Key Study

Cost Comparison

Estimated monthly costs compared to similar peptides

Peptide	Monthly Cost	FDA Status
GHRP-6	$35 - $70/mo	Not submitted
MK-677	$50 - $100/mo	Phase 2
CJC-1295	$35 - $70/mo	Not submitted
Ipamorelin	$35 - $70/mo	Not submitted
Sermorelin	$150 - $350/mo	FDA Approved

Medical Disclaimer

The information provided on this page is for educational and informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting, stopping, or modifying any peptide therapy or medication. PeptideVS does not endorse, recommend, or promote the use of any specific peptide for medical treatment. Clinical data cited may be from ongoing trials and is subject to change. Individual results may vary.