AOD-9604 vs Semax

A comprehensive, data-driven comparison of AOD-9604 (Advanced Obesity Drug) and Semax. Compare efficacy, side effects, costs, FDA approval status, and clinical evidence to make an informed decision.

AOD-9604
Phase 2 (failed; reclassification pending)
Fat loss and metabolism enhancement
Evidence
Low
Monthly Cost$30 - $60/mo
DosingDaily
Semax
Not submitted
Cognitive enhancement and neuroprotection
Evidence
Moderate
Monthly Cost$45 - $90/mo
DosingDaily

Side-by-Side Comparison

PropertyAOD-9604
Advanced Obesity Drug, Tyr-hGH Fragment 176-191
Semax
FDA Status
Phase 2 (failed; reclassification pending)
Not submitted
Category
Weight Loss
Cognitive Enhancement
Primary Use
Fat loss and metabolism enhancement
Cognitive enhancement and neuroprotection
Weight Loss %
N/A
N/A
Monthly Cost
$30 - $60/mo
$45 - $90/mo
Administration
Subcutaneous injection
Nasal spray
Typical Dose
300mcg daily
2-3 drops per nostril 2-3x daily
Frequency
Daily
Daily
Mechanism

Modified fragment of human growth hormone (amino acids 176-191) that stimulates lipolysis without affecting blood sugar or IGF-1

Synthetic ACTH analog that enhances BDNF production, improves cerebral circulation, and protects neurons

Common Side Effects
  • Injection site reactions
  • Headache
  • Chest tightness (rare)
  • Nasal irritation
  • Mild stimulation
  • Headache
  • Anxiety (at high doses)
Serious Side Effects
  • Unknown long-term effects
  • Potential interactions with growth hormone pathways
  • Unknown long-term effects
  • Potential sleep disturbances
Evidence Quality
Low
Moderate
Clinical Trial Phase
Phase 2
N/A

Key Differences

  • 1AOD-9604 is generally more affordable ($30 - $60/mo) compared to Semax ($45 - $90/mo).
  • 2AOD-9604 is administered via subcutaneous injection, while Semax uses nasal spray.
  • 3Semax has moderate-quality evidence, while AOD-9604 has low-quality evidence.
  • 4They belong to different categories: AOD-9604 (Weight Loss) vs Semax (Cognitive Enhancement).

Which Is Better For...

AO

AOD-9604

More budget-friendly option with lower monthly costs

AO

AOD-9604

Fewer commonly reported side effects

SE

Semax

Stronger clinical evidence base to support its use

Cost Comparison

PeptideMonthly Cost RangeFDA StatusManufacturer
AOD-9604$30 - $60/mo
Phase 2 (failed; reclassification pending)
Various research labs
Semax$45 - $90/mo
Not submitted
Various research labs

Prices are estimated monthly costs and may vary based on pharmacy, insurance coverage, and manufacturer assistance programs. Costs for non-FDA-approved peptides reflect research compound pricing.

Frequently Asked Questions

What is the main difference between AOD-9604 and Semax?

AOD-9604 works via Modified fragment of human growth hormone (amino acids 176-191) that stimulates lipolysis. Semax works via Synthetic ACTH analog that enhances BDNF production, improves cerebral circulation, and protects. They differ in FDA approval status, efficacy data, and cost.

How much does AOD-9604 cost compared to Semax?

AOD-9604 typically costs $30 - $60/mo, while Semax costs $45 - $90/mo. Prices may vary by pharmacy, insurance coverage, and manufacturer programs.

Are AOD-9604 and Semax FDA approved?

AOD-9604 is not FDA-approved (Phase 2 (failed; reclassification pending)). Semax is not FDA-approved (Not submitted). FDA approval indicates the treatment has met rigorous safety and efficacy standards.

What are the side effects of AOD-9604 vs Semax?

Common side effects of AOD-9604 include Injection site reactions, Headache, Chest tightness (rare). Common side effects of Semax include Nasal irritation, Mild stimulation, Headache. Always consult a healthcare provider about potential side effects.

Can I switch from AOD-9604 to Semax?

Switching between peptide therapies should only be done under the guidance of a qualified healthcare provider. They can evaluate your medical history, current response, and determine the safest transition protocol.

Learn More

AOD-9604 Full Profile
Fat loss and metabolism enhancement

AOD-9604 is a modified peptide fragment of the C-terminus of human growth hormone (amino acids 176-191). It was designed to retain the fat-burning properties of HGH while avoiding effects on blood sug...

View Full AOD-9604 Guide
Semax Full Profile
Cognitive enhancement and neuroprotection

Semax is a synthetic peptide analog of adrenocorticotropic hormone (ACTH) developed in Russia. It has been shown to increase brain-derived neurotrophic factor (BDNF), improve cerebral blood flow, and ...

View Full Semax Guide

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Medical Disclaimer

The information provided on this page is for educational and informational purposes only and does not constitute medical advice. This comparison between AOD-9604 and Semax should not be used as a substitute for professional medical guidance. Always consult a qualified healthcare provider before starting, stopping, or modifying any peptide therapy. Clinical data cited may be from ongoing trials and is subject to change. Individual results may vary significantly. PeptideVS does not endorse, recommend, or promote the use of any specific peptide for medical treatment.