AOD-9604 vs Melanotan II

A comprehensive, data-driven comparison of AOD-9604 (Advanced Obesity Drug) and Melanotan II (MT-2). Compare efficacy, side effects, costs, FDA approval status, and clinical evidence to make an informed decision.

AOD-9604
Phase 2 (failed; reclassification pending)
Fat loss and metabolism enhancement
Evidence
Low
Monthly Cost$30 - $60/mo
DosingDaily
Melanotan II
Not submitted
Tanning and sexual dysfunction (research)
Evidence
Low
Monthly Cost$30 - $60/mo
DosingAs needed

Side-by-Side Comparison

PropertyAOD-9604
Advanced Obesity Drug, Tyr-hGH Fragment 176-191
Melanotan II
MT-2, Melanotan 2
FDA Status
Phase 2 (failed; reclassification pending)
Not submitted
Category
Weight Loss
Sexual Health
Primary Use
Fat loss and metabolism enhancement
Tanning and sexual dysfunction (research)
Weight Loss %
N/A
N/A
Monthly Cost
$30 - $60/mo
$30 - $60/mo
Administration
Subcutaneous injection
Subcutaneous injection
Typical Dose
300mcg daily
0.25-1mg 2-3x per week
Frequency
Daily
As needed
Mechanism

Modified fragment of human growth hormone (amino acids 176-191) that stimulates lipolysis without affecting blood sugar or IGF-1

Melanocortin receptor agonist that stimulates melanogenesis for tanning and has effects on sexual arousal

Common Side Effects
  • Injection site reactions
  • Headache
  • Chest tightness (rare)
  • Nausea
  • Flushing
  • Spontaneous erections
  • Darkening of moles and freckles
  • +1 more
Serious Side Effects
  • Unknown long-term effects
  • Potential interactions with growth hormone pathways
  • New mole formation
  • Changes in existing moles
  • Cardiovascular effects
  • Unknown cancer risk
  • +2 more
Evidence Quality
Low
Low
Clinical Trial Phase
Phase 2
N/A

Key Differences

  • 1AOD-9604 is dosed daily, while Melanotan II is as needed.
  • 2They belong to different categories: AOD-9604 (Weight Loss) vs Melanotan II (Sexual Health).

Which Is Better For...

ME

Melanotan II

More convenient dosing schedule (as needed)

AO

AOD-9604

Fewer commonly reported side effects

Cost Comparison

PeptideMonthly Cost RangeFDA StatusManufacturer
AOD-9604$30 - $60/mo
Phase 2 (failed; reclassification pending)
Various research labs
Melanotan II$30 - $60/mo
Not submitted
Various research labs

Prices are estimated monthly costs and may vary based on pharmacy, insurance coverage, and manufacturer assistance programs. Costs for non-FDA-approved peptides reflect research compound pricing.

Frequently Asked Questions

What is the main difference between AOD-9604 and Melanotan II?

AOD-9604 works via Modified fragment of human growth hormone (amino acids 176-191) that stimulates lipolysis. Melanotan II works via Melanocortin receptor agonist that stimulates melanogenesis for tanning and has effects on. They differ in FDA approval status, efficacy data, and cost.

How much does AOD-9604 cost compared to Melanotan II?

AOD-9604 typically costs $30 - $60/mo, while Melanotan II costs $30 - $60/mo. Prices may vary by pharmacy, insurance coverage, and manufacturer programs.

Are AOD-9604 and Melanotan II FDA approved?

AOD-9604 is not FDA-approved (Phase 2 (failed; reclassification pending)). Melanotan II is not FDA-approved (Not submitted). FDA approval indicates the treatment has met rigorous safety and efficacy standards.

What are the side effects of AOD-9604 vs Melanotan II?

Common side effects of AOD-9604 include Injection site reactions, Headache, Chest tightness (rare). Common side effects of Melanotan II include Nausea, Flushing, Spontaneous erections. Always consult a healthcare provider about potential side effects.

Can I switch from AOD-9604 to Melanotan II?

Switching between peptide therapies should only be done under the guidance of a qualified healthcare provider. They can evaluate your medical history, current response, and determine the safest transition protocol.

Learn More

AOD-9604 Full Profile
Fat loss and metabolism enhancement

AOD-9604 is a modified peptide fragment of the C-terminus of human growth hormone (amino acids 176-191). It was designed to retain the fat-burning properties of HGH while avoiding effects on blood sug...

View Full AOD-9604 Guide
Melanotan II Full Profile
Tanning and sexual dysfunction (research)

Melanotan II is a synthetic analog of alpha-melanocyte stimulating hormone that binds to melanocortin receptors. Originally developed for skin tanning protection against UV damage, it was found to hav...

View Full Melanotan II Guide

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Medical Disclaimer

The information provided on this page is for educational and informational purposes only and does not constitute medical advice. This comparison between AOD-9604 and Melanotan II should not be used as a substitute for professional medical guidance. Always consult a qualified healthcare provider before starting, stopping, or modifying any peptide therapy. Clinical data cited may be from ongoing trials and is subject to change. Individual results may vary significantly. PeptideVS does not endorse, recommend, or promote the use of any specific peptide for medical treatment.