Sexual Health
Not submitted
Evidence: Low / Preclinical

Melanotan II

Also known as: MT-2, Melanotan 2

Overview
Tanning and sexual dysfunction (research)

Melanotan II is a synthetic analog of alpha-melanocyte stimulating hormone that binds to melanocortin receptors. Originally developed for skin tanning protection against UV damage, it was found to have significant effects on sexual arousal and erectile function. Development was discontinued due to side effects and regulatory concerns. It is not FDA-approved.

Mechanism of Action

Melanocortin receptor agonist that stimulates melanogenesis for tanning and has effects on sexual arousal

Dosage Information
ParameterDetail
AdministrationSubcutaneous injection
Typical Dose0.25-1mg 2-3x per week
FrequencyAs needed
Side Effects
Reported adverse effects from clinical data and post-market surveillance

Common Side Effects

Nausea
Flushing
Spontaneous erections
Darkening of moles and freckles
Yawning

Serious Side Effects

New mole formation
Changes in existing moles
Cardiovascular effects
Unknown cancer risk
!Contraindications
Do not use this peptide if any of the following apply
  • Pregnancy
  • Personal or family history of melanoma
  • Cardiovascular disease
  • Children
Clinical Evidence

Evidence Quality

Low / Preclinical

Clinical Trial Phase

Preclinical / Not submitted

Cost Comparison
Estimated monthly costs compared to similar peptides
PeptideMonthly CostFDA Status
Melanotan II$30 - $60/mo
Not submitted
PT-141$800 - $1200/mo
FDA Approved

Medical Disclaimer

The information provided on this page is for educational and informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting, stopping, or modifying any peptide therapy or medication. PeptideVS does not endorse, recommend, or promote the use of any specific peptide for medical treatment. Clinical data cited may be from ongoing trials and is subject to change. Individual results may vary.