Ipamorelin vs AOD-9604

A comprehensive, data-driven comparison of Ipamorelin (NNC 26-0161) and AOD-9604 (Advanced Obesity Drug). Compare efficacy, side effects, costs, FDA approval status, and clinical evidence to make an informed decision.

Ipamorelin
Category 2 (pending reclassification)
Growth hormone optimization
Evidence
Emerging
Monthly Cost$35 - $70/mo
DosingDaily
AOD-9604
Phase 2 (failed; reclassification pending)
Fat loss and metabolism enhancement
Evidence
Low
Monthly Cost$30 - $60/mo
DosingDaily

Side-by-Side Comparison

PropertyIpamorelin
NNC 26-0161
AOD-9604
Advanced Obesity Drug, Tyr-hGH Fragment 176-191
FDA Status
Category 2 (pending reclassification)
Phase 2 (failed; reclassification pending)
Category
Growth Hormone
Weight Loss
Primary Use
Growth hormone optimization
Fat loss and metabolism enhancement
Weight Loss %
N/A
N/A
Monthly Cost
$35 - $70/mo
$30 - $60/mo
Administration
Subcutaneous injection
Subcutaneous injection
Typical Dose
200-300mcg 2-3x daily
300mcg daily
Frequency
Daily
Daily
Mechanism

Selective growth hormone secretagogue that binds to ghrelin receptors to stimulate GH release without affecting cortisol or prolactin

Modified fragment of human growth hormone (amino acids 176-191) that stimulates lipolysis without affecting blood sugar or IGF-1

Common Side Effects
  • Injection site reactions
  • Increased hunger
  • Headache
  • Mild water retention
  • Injection site reactions
  • Headache
  • Chest tightness (rare)
Serious Side Effects
  • Potential insulin resistance
  • Unknown long-term effects
  • Unknown long-term effects
  • Potential interactions with growth hormone pathways
Evidence Quality
Emerging
Low
Clinical Trial Phase
N/A
Phase 2

Key Differences

  • 1AOD-9604 is generally more affordable ($30 - $60/mo) compared to Ipamorelin ($35 - $70/mo).
  • 2AOD-9604 has low-quality evidence, while Ipamorelin has emerging-quality evidence.
  • 3They belong to different categories: Ipamorelin (Growth Hormone) vs AOD-9604 (Weight Loss).

Which Is Better For...

AO

AOD-9604

More budget-friendly option with lower monthly costs

AO

AOD-9604

Fewer commonly reported side effects

AO

AOD-9604

Stronger clinical evidence base to support its use

Cost Comparison

PeptideMonthly Cost RangeFDA StatusManufacturer
Ipamorelin$35 - $70/mo
Category 2 (pending reclassification)
Various research labs
AOD-9604$30 - $60/mo
Phase 2 (failed; reclassification pending)
Various research labs

Prices are estimated monthly costs and may vary based on pharmacy, insurance coverage, and manufacturer assistance programs. Costs for non-FDA-approved peptides reflect research compound pricing.

Frequently Asked Questions

What is the main difference between Ipamorelin and AOD-9604?

Ipamorelin works via Selective growth hormone secretagogue that binds to ghrelin receptors to stimulate GH. AOD-9604 works via Modified fragment of human growth hormone (amino acids 176-191) that stimulates lipolysis. They differ in FDA approval status, efficacy data, and cost.

How much does Ipamorelin cost compared to AOD-9604?

Ipamorelin typically costs $35 - $70/mo, while AOD-9604 costs $30 - $60/mo. Prices may vary by pharmacy, insurance coverage, and manufacturer programs.

Are Ipamorelin and AOD-9604 FDA approved?

Ipamorelin is not FDA-approved (Category 2 (pending reclassification)). AOD-9604 is not FDA-approved (Phase 2 (failed; reclassification pending)). FDA approval indicates the treatment has met rigorous safety and efficacy standards.

What are the side effects of Ipamorelin vs AOD-9604?

Common side effects of Ipamorelin include Injection site reactions, Increased hunger, Headache. Common side effects of AOD-9604 include Injection site reactions, Headache, Chest tightness (rare). Always consult a healthcare provider about potential side effects.

Can I switch from Ipamorelin to AOD-9604?

Switching between peptide therapies should only be done under the guidance of a qualified healthcare provider. They can evaluate your medical history, current response, and determine the safest transition protocol.

Learn More

Ipamorelin Full Profile
Growth hormone optimization

Ipamorelin is a pentapeptide that selectively stimulates growth hormone release by mimicking ghrelin, the hunger hormone. Unlike many other GH secretagogues, ipamorelin does not significantly increase...

View Full Ipamorelin Guide
AOD-9604 Full Profile
Fat loss and metabolism enhancement

AOD-9604 is a modified peptide fragment of the C-terminus of human growth hormone (amino acids 176-191). It was designed to retain the fat-burning properties of HGH while avoiding effects on blood sug...

View Full AOD-9604 Guide

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Medical Disclaimer

The information provided on this page is for educational and informational purposes only and does not constitute medical advice. This comparison between Ipamorelin and AOD-9604 should not be used as a substitute for professional medical guidance. Always consult a qualified healthcare provider before starting, stopping, or modifying any peptide therapy. Clinical data cited may be from ongoing trials and is subject to change. Individual results may vary significantly. PeptideVS does not endorse, recommend, or promote the use of any specific peptide for medical treatment.