Anti-Aging
Not submitted
Evidence: Moderate

GHK-Cu

Also known as: Copper Peptide, GHK-Copper

Overview
Skin rejuvenation and anti-aging

GHK-Cu is a naturally occurring copper-binding peptide found in human plasma that declines with age. It has been extensively studied for skin rejuvenation due to its ability to stimulate collagen and elastin production, improve skin elasticity, and reduce fine lines and wrinkles. GHK-Cu is available in topical formulations and injectable forms.

Mechanism of Action

Naturally occurring copper complex that stimulates collagen production, promotes tissue remodeling, and has antioxidant properties

Dosage Information
ParameterDetail
AdministrationTopical
Typical Dose1-2% topical cream daily, or 1-2mg injection
FrequencyDaily
Side Effects
Reported adverse effects from clinical data and post-market surveillance

Common Side Effects

Mild skin irritation (topical)
Injection site reactions
Temporary copper taste

Serious Side Effects

Copper toxicity (rare, with excessive use)
Allergic reactions
!Contraindications
Do not use this peptide if any of the following apply
  • Wilson disease
  • Copper sensitivity
  • Pregnancy
Clinical Evidence

Evidence Quality

Moderate

Clinical Trial Phase

Preclinical / Not submitted

Cost Comparison
Estimated monthly costs compared to similar peptides
PeptideMonthly CostFDA Status
GHK-Cu$25 - $60/mo
Not submitted
Epithalon$40 - $80/mo
Not submitted

Medical Disclaimer

The information provided on this page is for educational and informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting, stopping, or modifying any peptide therapy or medication. PeptideVS does not endorse, recommend, or promote the use of any specific peptide for medical treatment. Clinical data cited may be from ongoing trials and is subject to change. Individual results may vary.